Finite Element Analysis of Bone-Derived Hydroxyapatite, Zinc-Doped Hydroxyapatite, and PLGA–Zn-HAp Composites for Biomedical Applications

Autores/as

  • M Saravanan Department of Mechanical Engineering, Aarupadai Veedu Institute of Technology, Vinayaka Mission’s Research Foundation (DU), Tamil Nadu, India.
  • Abhijith J Department of Mechanical Engineering, Aarupadai Veedu Institute of Technology, Vinayaka Mission’s Research Foundation (DU), Tamil Nadu, India.
  • Sangeetha Krishnamoorthi Department of Mechanical Engineering, Aarupadai Veedu Institute of Technology, Vinayaka Mission’s Research Foundation (DU), Tamil Nadu, India.
  • Athira Kishore M.D. Scholar - Department of Practice of Medicine, National Homoeopathy Research Institute in Mental Health – NHRIMH, Kottayam, Kerala 686532
  • Saravana Kumar.M Department of Mechanical Engineering, Aarupadai Veedu Institute of Technology, Vinayaka Mission’s Research Foundation (DU), Tamil Nadu, India

DOI:

https://doi.org/10.5935/jetia.v12i60.3354

Resumen

Bone-derived hydroxyapatite (HAp) is highly biocompatible but lacks mechanical strength. This study addresses this limitation by adding zinc (Zn) and poly (lactic-co-glycolic acid) (PLGA) to enhance performance. We synthesised goat-bone HAp via calcination and chemical treatment, incorporated Zn to improve crystallinity and antibacterial activity, and reinforced it with PLGA for better flexibility and load-bearing capacity. Finite element modelling in ANSYS (100–1000 N loading) showed that pure HAp is stiff but brittle, Zn-HAp is stronger, and the PLGA-Zn-HAp composite has the greatest toughness, stress distribution, and fracture resistance. Simulations closely matched experiments, confirming that Zn and PLGA strengthen natural HAp and make the composite a promising, cost-effective choice for orthopaedic implants.

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Publicado

2026-07-31

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Cómo citar

Finite Element Analysis of Bone-Derived Hydroxyapatite, Zinc-Doped Hydroxyapatite, and PLGA–Zn-HAp Composites for Biomedical Applications. (2026). ITEGAM-JETIA, 12(60), 49-56. https://doi.org/10.5935/jetia.v12i60.3354

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