High Sensitive 2D Photonic Crystal Biosensor Based on Hexagonal Resonator Coupled with a Capsule-Shaped for the Detection of Deferent Cancerous Cells

Resumen

In the present study, we introduce an innovative photonic crystal architecture meticulously engineered for biomedical applications, particularly optimized for biosensing functionalities. Our study focuses on meeting the increasing demand for quick, reliable, and easy-to-use detection methods in medical diagnostics. The proposed architecture employs a hexagonal arrangement integrated with two waveguides for signal input and output, which is further augmented by the inclusion of a pill-shaped resonator to enhance sensitivity. The design enables strong confinement of the electromagnetic field and improves interaction with the analyte. The simulations were performed using the Finite-Difference Time-Domain (FDTD) method over a wavelength range of 1.6 to 1.95 micrometers (µm). The findings indicate that the biosensor is capable of attaining a peak sensitivity of 571 nanometers per refractive index unit (nm/RIU), thereby underscoring its significant potential for detecting subtle alterations in biological specimens and contributing to the advancement of medical diagnostics. Such sensitivity levels demonstrate the effectiveness of the proposed structure in identifying biomolecular interactions and refractive index variations typically associated with various types of cancer cells and other biological conditions.