Antifungal effectiveness test fragrant leaf ethanol extract (Pandanus Amaryllifolium Robx) against fungus Pityrosporum Ovale in vitro

Angelika Sinaga; Saadah Siregar; Vincentia Ade Rizky; Riana Topia

doi:10.5935/jetia.v7i31.773

Autores

Angelika Sinaga Faculdade de Farmácia, Institut Kesehatan Medistra Lubuk Pakam, Jl. Sudirman No.38, Lubuk Pakam, Delhi Serdang 20512, North Sumatra, Indonésia http://orcid.org/0000-0001-9488-9063 (não autenticado)
Saadah Siregar Tecnologia de Laboratório Médico, Faculdade de Farmácia, Institut Kesehatan Medistra Lubuk Pakam, Jl. Sudirman No.38, Lubuk Pakam, Deli Serdang 20512, North Sumatra, Indonésia http://orcid.org/0000-0002-0664-4873 (não autenticado)
Vincentia Ade Rizky Tecnologia de Laboratório Médico, Faculdade de Farmácia, Institut Kesehatan Medistra Lubuk Pakam, Jl. Sudirman No.38, Lubuk Pakam, Deli Serdang 20512, North Sumatra, Indonésia http://orcid.org/0000-0002-2866-1236 (não autenticado)
Riana Topia Programa de Pós-Graduação em Farmácia, Faculdade de Farmácia, Institut Kesehatan Medistra Lubuk Pakam, Jl. Sudirman No.38, Lubuk Pakam, Deli Serdang 20512, North Sumatra, Indonésia http://orcid.org/0000-0001-5580-1647 (não autenticado)

DOI:

https://doi.org/10.5935/jetia.v7i31.773

Resumo

A caspa é um dos problemas de infecção fúngica que causa falta de confiança e desconforto devido às queixas de coceira que a acompanha. O fungo que causa a caspa é o Pityrosporum ovale. Foi relatado que Pityrosporum ovale é resistente ao uso dessas drogas azólicas. Uma das plantas com potencial como fitoterapia são as folhas de pandan (Pandanus amaryllifolius Roxb). O objetivo deste estudo foi determinar a atividade antifúngica do extrato fragrante da folha de pandan (Pandanus amaryllifolius Roxb) sobre o crescimento de Pityrosporum ovale in vitro. O método de pesquisa utilizado um método experimental com as concentrações de extrato utilizadas foram 10%, 20%, 30% e 40%. O método de teste antifúngico usa o método de difusão em ágar usando o método de Kirby Bauer. Os resultados mostraram que o extrato da folha com fragrância de pandan com concentrações de 10%, 20%, 30% e 40% apresentou inibição antifúngica moderada contra Pityrosporum ovale. A maior zona de inibição estava na concentração de 40%, que era de 9,43 mm. Isso indica que o extrato de folha de pandan fragrante tem efeito antifúngico sobre Pityrosporum ovale que causa caspa. Para que os resultados deste estudo possam ser usados como um produto para reduzir o problema da caspa.

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